Diffuse parenchymal lung disease

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DIFFUSE PARENCHYMAl lUNG DISEASE

Diffuse parenchymal lung disease (DPLD) is a group of diseases that have the common characteristic of involving the pulmonary parenchyma diffusely. The pulmonary parenchyma consists of all structures distal to the terminal bronchiole. DPLD are numerous, there are some 150 different entities that qualify for the group. Most of these diseases are diagnosed according to common algorithm, but the e...

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Intrathoracic involvement is common in Castleman disease (CD), but CD-associated diffuse parenchymal lung disease (DPLD) is rare and not well-reported.We conducted a retrospective analysis of 262 CD patients with a definite pathological diagnosis who were hospitalized between 1999 and 2015.Twenty-two CD patients had DPLD based on chest computed tomography (CT) scans. Among them, 9 were male and...

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Genetic testing in diffuse parenchymal lung disease

Diffuse parenchymal lung diseases (DPLD) represent a diverse group of disorders affecting the distal lung parenchyma, specifically the tissue and spaces surrounding the alveoli, which may be filled with inflammatory cells, proliferating fibroblasts or established fibrosis, often leading to architectural distortion and impaired gas exchange. While the underlying pathogenetic mechanisms are known...

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Categorizing diffuse parenchymal lung disease in children

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ژورنال

عنوان ژورنال: European Respiratory Review

سال: 2017

ISSN: 0905-9180,1600-0617

DOI: 10.1183/16000617.0004-2017